NueCog Methylene Blue | USP Grade, UK Formulated, Third-Party Tested

NueCog formulates Methylene Blue for laboratory and in-vitro research applications, formulated and encapsulated in the UK to research-grade standards with independent third-party batch testing.

Methylene Blue (3,7-bis(dimethylamino)phenothiazin-5-ium chloride) is one of the most extensively studied synthetic compounds in biomedical research, with a scientific record spanning over 130 years. As a redox-active phenothiazine dye, it is uniquely capable of cycling between its oxidised (blue) and reduced (colourless) states — a property that underpins its broad utility as an electron carrier and mitochondrial research tool.

Why Researchers Choose NueCog Methylene Blue

  • •  Verified purity — ≥99% USP grade (HPLC verified), with a Certificate of Analysis available for every batch on request.
  • •  UK-formulated — formulated and encapsulated under controlled quality protocols, not relabelled or imported from unverified sources.
  • •  Consistent supply — the product researchers reorder is the same one they tested with previously.

Research Background

Methylene Blue is one of the few compounds with documented activity across mitochondrial, neurological, and antimicrobial research domains. Active areas of scientific investigation include:

  • •  Mitochondrial function — acts as an alternative electron carrier between NADH and cytochrome c, supporting Complex IV activity and oxygen consumption.
  • •  Neuroprotection research — explored in models of Alzheimer's, Parkinson's, and traumatic brain injury for its ability to enhance mitochondrial resilience and reduce oxidative stress.
  • •  Cognitive and memory research — preclinical studies examining its influence on memory consolidation and cerebral metabolic rate.
  • •  Hormesis modelling — well-documented biphasic dose-response behaviour, making it a valuable tool in hormesis and dose-dependency research.
  • •  Antimicrobial and photodynamic applications — long-established use in antimicrobial research, including photodynamic inactivation of pathogens.
  • •  Cellular redox biology — widely used as a redox indicator and in studies of oxidative stress, ROS generation, and antioxidant defence systems.

This section is for research and educational reference only. NueCog Methylene Blue is not intended for human consumption, veterinary use, diagnostic application, or any therapeutic use, and none of the above constitutes usage guidance.

Quality Assurance

NueCog Methylene Blue is supplied at USP-grade purity. Every batch undergoes third-party analytical testing. Certificate of Analysis (CoA) available on request. All products are manufactured to research-grade standards under strict quality control protocols.

Intended Use

This product is sold strictly for laboratory and in-vitro research purposes only. It is not intended for human consumption, veterinary use, or diagnostic application. Not for sale to minors. This product is not a medicine, food supplement, or drug.