5-AMINO-1MQ

5-Amino-1MQ is a selective, membrane-permeable small molecule inhibitor of Nicotinamide N-Methyltransferase (NNMT) — an enzyme increasingly recognised for its role in metabolic regulation, adipogenesis, and cellular NAD⁺ homeostasis.

Product Specifications

Research Background

NNMT is highly expressed in adipose tissue and functions as a key regulator of the methyl economy within cells. Selective inhibition with 5-Amino-1MQ has been explored across a range of preclinical research contexts, including:

• •  Adipocyte metabolism — reduction of fat cell size and lipid accumulation in in-vitro models.
• •  NAD⁺ pathway modulation — restoration of SAM and NAD⁺ precursor availability via NNMT suppression.
• •  Epigenetic regulation — influence on histone methylation patterns linked to metabolic gene expression.
• •  Obesity and diet-induced metabolic dysfunction — preclinical models examining weight regulation and insulin sensitivity.
• •  Cellular senescence — emerging research into NNMT's role in ageing-associated metabolic decline.

Quality Assurance

Every batch of NueCog 5-Amino-1MQ undergoes third-party analytical testing. Certificate of Analysis (CoA) available on request. All products are manufactured to research-grade standards under strict quality control protocols.

Read more in our NueCog 5-Amino-1MQ Research Guide.

Intended Use

This product is sold strictly for laboratory and in-vitro research purposes only. It is not intended for human consumption, veterinary use, or diagnostic application. Not for sale to minors. This product is not a medicine, food supplement, or drug.